Protein folding and misfolding: neurodegenerative diseases by Ferenc Orosz (Engl-image

Protein folding and misfolding: neurodegenerative diseases by Ferenc Orosz (Engl

$ 141.32

Publication Name: Protein Folding and Misfolding : Neurodegenerative Diseases Book Title: Protein folding and misfolding: neurodegenerative diseases Item Weight: 17.6 Oz Subject Area: Science, Medical ISBN-13: 9789048181278 Publisher: Springer Netherlands Item Length: 9.3 in Author: Ferenc Orosz Type: Textbook Country of Origin: United States Format: Trade Paperback Language: English ISBN: 9789048181278 Publication Year: 2010 Series: Focus on Structural Biology Ser. Subject: Life Sciences / Neuroscience, Life Sciences / Cell Biology, Research Item Width: 6.1 in Number of Pages: Xiv, 278 Pages gtin13: 9789048181278

Description

Protein folding and misfolding: neurodegenerative diseases by Ferenc Orosz, Judit Ovádi Estimated delivery 3-12 business days Format Paperback Condition Brand New Description Offering all the latest in the study of neurodegenerative diseases, this book reviews the molecular events initiated by unfolded or misfolded proteins leading to conformational human diseases, especially those found in Parkinson's and Alzheimer's diseases. Publisher Description It was twenty ?ve years ago this year that for the ?rst time a protein under- ing a form of human cerebral amyloidosis, the Icelandic-type hereditary cerebral haemorrhage was identi?ed. This, together with the recognition that an amino acid substitution can transform the wild type cystatin C into a disease-associated amyloid-forming protein in this condition, was only a prelude to a series of imp- tant discoveries that followed. As a result, pathologically altered proteins have been brought into the centre stage of research into the pathomechanism of a n- ber of neurodegenerative diseases, which include epidemiologically such important conditions as Alzheimer's disease or Parkinson's disease and, among others, also the transmissible spongiform encephalopathies, Huntington's chorea, spinocereb- lar ataxias, frontotemporal lobar degenerations and amyotrophic lateral sclerosis.Despite the diversity in the amino acid sequence of the different proteins involved in these neurological diseases, one of the common themes underlying the patho- chanisms of all these conditions is protein misfolding, aggregation - hence the term protein folding disorders -, which can trigger cascades of events ultimately resulting in synapse loss and neuron death with devastating clinical consequences in many of the most precious spheres of human existence including personality, cognition, memory, skilled movements and affection. It is always a challenging task to unite the different topics of the individual ch- ters into a common theme in a multi-author volume, but the current book edited by Judit Ovadi and Ferenc Orosz ?ts this task admirably. Details ISBN 9048181275 ISBN-13 9789048181278 Title Protein folding and misfolding: neurodegenerative diseases Author Ferenc Orosz, Judit Ovádi Format Paperback Year 2010 Pages 278 Edition 1st Publisher Springer GE_Item_ID:48369746; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

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    user17014857

  2. Like new condition, safe packaging, good communication from seller. Fair price for the quality. Shipping was on time, but tracking information took over a week to receive. The book was as-described with minor cosmetic flaws (indentations in some pages, for example). I wish the listings showed the actual item being sold to you instead of just an accurate stock photo. This edition and appearance of George Orwell's 1984 here is a nice pocket-sized hardcover. I would buy from this shop again.

    JeffsHousecf

  3. The two new out-of-print books I ordered were exactly as described and shipped promptly. I did ask the seller's support person (an AI chatbot, I think) to be sure to package the items carefully, and "he" said that he'd make that request of the shipping department. I knew this was hooey, and as I expected, the books were shipped in nothing but a padded paper mailer, no other protection. I got lucky, no damage, but don't bother making special requests of this seller.

    Olivier Marguillard

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