Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and A
$ 135.21
Description
Anticancer Drug Development Guide by Beverly A. Teicher, Paul A. Andrews Estimated delivery 3-12 business days Format Paperback Condition Brand New Description Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of "antileukemia" agents, but that other tumor models would be needed to discover drugs active against solid tumors. Publisher Description This unique volume traces the critically important pathway by which a "molecule" becomes an "anticancer agent. " The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these "anticancer" molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening methods. The National Cancer Institute's high-throughput, in vitro disease-specific screen with 60 or more human tumor cell lines is used to search for molecules with novel mechanisms of action or activity against specific phenotypes. The Human Tumor Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of cells that more nearly resemble the human disease. There is no doubt that the greatest successes of traditional chemotherapy have been in the leukemias and lymphomas. Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of "antileukemia" agents, but that other tumor models would be needed to discover drugs active against solid tumors. Details ISBN 146849841X ISBN-13 9781468498417 Title Anticancer Drug Development Guide Author Beverly A. Teicher, Paul A. Andrews Format Paperback Year 2012 Pages 451 Publisher Humana Press Inc. GE_Item_ID:137806754; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys
Seller sent me the wrong book, but the book they sent sounded interesting enough for me to keep it. I still contacted the seller and communication was fast and professional. They apologized for sending me the wrong book and said I could return it for a refund. I told them that I liked the book they sent me and wanted to keep it. They were happy. Told them thank you and happy new year. People make mistakes, but the fact that this seller was quick and professional and apologized made a difference.
The basket is perfectly what I ordered and as listed. It came in the factory packaging and was perfect upon delivery. Thank you postal service lol. The delivery took way longer than listed though, it was listed to come in a week from purchase, but took a whole month. I had some concerns at first, but communication with the company was top notch and they were very professional and answered most of my questions satisfyingly. Just prepare for a longer wait than listed, but I got what I bought lol.
The two new out-of-print books I ordered were exactly as described and shipped promptly. I did ask the seller's support person (an AI chatbot, I think) to be sure to package the items carefully, and "he" said that he'd make that request of the shipping department. I knew this was hooey, and as I expected, the books were shipped in nothing but a padded paper mailer, no other protection. I got lucky, no damage, but don't bother making special requests of this seller.
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