Development of zolmitriptan niosomalin-situ nasal gel by Anilkumar Shinde Paperb
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Description
Development of zolmitriptan niosomalin-situ nasal gel by Anilkumar Shinde Paperb. Optimized niosomal formulation was used for preparation of in situ gel formulation. The FTIR and DSC studies predicted that there was no chemical interaction between drug and excipients. Author Anilkumar Shinde, Karan Swami, Firoj Tamboli. Development of zolmitriptan niosomalin-situ nasal gel by Anilkumar Shinde, Karan Swami, Firoj Tamboli Estimated delivery 3-12 business days Format Paperback Condition Brand New Description The objective of the present investigation was to development of Zolmitriptan (ZMT) niosomal in-situ nasal gel formulation for treatment of migraine. The intranasal route could delivered drug to the central nervous system (CNS) through the olfactory lobes, which helps to circumvent the blood brain barrier (BBB), which bypasses first pass metabolism and consequently enhances the bioavailability of the drug. ZMT niosomes were prepared using lipid film hydration technique. Optimized niosomal formulation was used for preparation of in situ gel formulation. The developed formulations were characterized for vesicle size, shape, zeta potential, entrapment efficiency, drug content and in-vitro diffusion study, mucoadhesive strength, permeation study, FTIR, DSC and XRD studies. The FTIR and DSC studies predicted that there was no chemical interaction between drug and excipients. ZMT niosomes were showed particle size, PDI, Zeta potential, % entrapment efficiency and drug content, 149nm, 0.223, -28.9, 88.16±0.8 % and 96.23±1.2% respectively. In vitro diffusion study of niosomes shows 96.23±0.7% at 8h. The permeation rate of in situ niosomes gel and pure drug was about 98.56% and 79.46%. Details ISBN 6209119247 ISBN-13 9786209119248 Title Development of zolmitriptan niosomalin-situ nasal gel Author Anilkumar Shinde, Karan Swami, Firoj Tamboli Format Paperback Year 2025 Pages 56 Publisher LAP Lambert Academic Publishing GEItemID:175482168; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys
